03/15/08 8am (8pm Beijing time)

9. Supratentorial PNET 幕上的PNET

KEY WORDS

PNET = primitive neuroectodermal tumor

Rosette

Homer-Wright rosette

Neuroblastic rosette

Flexner-Wintersteiner rosette

Retinoblastoma

Photoreceptor cell (rod and cone)

True ependymal rosette

Ependymal canal

Perivascular (pseudo)rosette

Pineocytomatous rosette

Neurocytic rosette

Divergent differentiation

CD56 (NCAM) = neural cell adhesion molecule

Ganglioneuroblastoma

Small cell glioblastoma

REFERENCE:

http://www.ajnr.org/cgi/content/full/27/3/488

 fig1 Photomicrograph from a PNET demonstrating multiple Homer Wright rosettes. The halo-like cluster of cells in each rosette surrounds a central area of fiber-rich neuropil (H&E; original magnification 400x).

fig2 Photomicrograph from a retinoblastoma showing multiple Flexner-Wintersteiner rosettes. The halo-like cluster of cells in each rosette surrounds a nearly empty appearing central lumen containing fine cytoplasmic processes (H&E; original magnification 400x). Photomicrograph generously donated by Dr. Morton Smith, Ophthalmic Pathology, Washington University, St. Louis.

fig3 Photomicrograph from an ependymoma showing several true ependymal rosettes. The halo-like cluster of cells in each rosette surrounds an empty central lumen (H&E; original magnification 400x).

fig 4 Photomicrograph from an ependymoma showing 2 prominent perivascular pseudorosettes. The halo-like cluster of cells in each rosette surrounds a blood vessel. Note the several smaller true ependymal rosettes (H&E; original magnification 200x).

fig5 Photomicrograph from a central neurocytoma containing an irregularly shaped neurocytic rosette with central neuropil (H&E; original magnification 400x).

http://http://www.ajnr.org/cgi/content/full/27/3/488