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Neutrophils are seen in all Pap samples and do not necessarily indicate infection, but they are present in increased numbers after injury or infection. Lymphocytes and plasma cells are rare, but occasionally—most often in older women—they are numerous (Figs. 1.16, 1.71A). This pattern is called follicular cervicitis because biopsies show lymphoid follicle formation. The lymphocytes of follicular cervicitis can be confused with HSIL cells, endometrial cells, and lymphoma. Histiocytes are associated with a myriad of conditions (e.g., menses, pregnancy, foreign bodies, radiotherapy, and endometrial hyperplasia and carcinoma) (Fig. 1.17), but by themselves are a nonspecific finding of no clinical significance.
Neutrophils are seen in all Pap samples and do not necessarily indicate infection, but they are present in increased numbers after injury or infection. Lymphocytes and plasma cells are rare, but occasionally—most often in older women—they are numerous (Figs. 1.16, 1.71A). This pattern is called follicular cervicitis because biopsies show lymphoid follicle formation. The lymphocytes of follicular cervicitis can be confused with HSIL cells, endometrial cells, and lymphoma. Histiocytes are associated with a myriad of conditions (e.g., menses, pregnancy, foreign bodies, radiotherapy, and endometrial hyperplasia and carcinoma) (Fig. 1.17), but by themselves are a nonspecific finding of no clinical significance.
在所有液基标本中见可见到中性粒细胞,并不一定说明是感染,中性粒细胞可在损伤或感染后数量增加。淋巴细胞和浆细胞少见,但有时(多见于老年女性)数量增多,组织学上可见淋巴样滤泡,因此这种类型称为滤泡性宫颈炎。宫颈淋巴滤泡有时会与HSIL细胞,子宫内膜细胞和淋巴瘤细胞相混淆,组织细胞的出现与多种因素相关(如经期、妊娠、异物、放射治疗、子宫内膜增生症和癌),但这些都没有特殊的临床意义。