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Sixty old man with proteinuria and hematuria

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楼主 发表于 2011-08-01 22:45|举报|关注(0)
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  • Sixty old man with proteinuria and hematuria图1
    图1
  • Sixty old man with proteinuria and hematuria图2
    图2
  • Sixty old man with proteinuria and hematuria图3
    图3
  • Sixty old man with proteinuria and hematuria图4
    图4
  • Sixty old man with proteinuria and hematuria图5
    图5
  • Sixty old man with proteinuria and hematuria图6
    图6
  • Sixty old man with proteinuria and hematuria图7
    图7
  • Sixty old man with proteinuria and hematuria图8
    图8
  • Sixty old man with proteinuria and hematuria图9
    图9
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本帖最后由 quhong 于 2011-08-01 22:46:54 编辑
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1 楼    发表于2011-08-15 09:55:36举报|引用
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本帖最后由 quhong 于 2011-08-15 09:59:00 编辑
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 Here are the additional EM photos with high magnification:

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2 楼    发表于2011-08-20 10:55:10举报|引用
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Picture 2 you fisrt posting showed a lot of foamy cells and some things like HP  in a tubular cavity in the centre of picture. About picture 7, i can see one capillary loop and its endothelial cell, i'm doute of  like a tadpole someting different in the capillary cavity , can you tell me, thank you very much.

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2 楼    发表于2011-08-23 04:06:12举报|引用
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 Yes, I agree with your observation that there are a lot of foamy cells. The most impressive change is the lamination or splitting of the glomerular basement membrane.

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3 楼    发表于2011-08-23 04:08:53举报|引用
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 In the photo #7, there are three platelets in the capillary lumen. I don't know their significance.

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3 楼    发表于2011-08-23 04:08:59举报|引用
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 In the photo #7, there are three platelets in the capillary lumen. I don't know their significance.

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3 楼    发表于2011-08-24 09:28:35举报|引用
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Thank you,to combine the splitting of the glomerular basement membrane with a lot of foamy cells infiltration, I first take into account Alport Syndrome, but the age of the patient is too old, so Alport Syndrome seems unlikely. Under LM, the glomerulosclerosis and tubular atrophy/interstitial fibrosis. Please comment, thank you

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4 楼    发表于2011-08-25 22:48:10举报|引用
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 The patient has a long history of "chronic kidney disease". Initially, he did not tell the nephrologist that he started to have kidney disease decades ago. Given the characteristic ultrastructural changes, Alport's syndrome is suggested.

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