This is a very interesting case. Please provide couple low power pictures, especially the junction between this "change" from the normal. I see some foamy histiocytes in second picture. Presence of foamy histiocytes in EM biopsy is always the alarming sign and should rule out pathologic abnormality.  Another important clinical symptom is that she is presumably PMD (postmenopausal bleeding). If she is PMD, secretory change can be rule out. I will provide further discussion when I see more photos of this case.

Thank 千百和 for sharing this case with us.

[这是很有意义的病例，请提供相应的低倍图，特别是此“改变”与正常结构之间的移行区域。第二图见到泡沫状组织细胞，它在内膜活检中出现通常是引起警惕的信号，应排除病理学异常。另外，根据临床资料推测为绝经后出血（PMD）。如果是PMD，可以排除分泌性改变。如果提供更多图，我会进一步讨论。
谢谢千百合与我们分享此例。     abin译]

好的,我明天去弄图去.沈阳给诊断的是低度恶性肿瘤,考虑是中肾管来源

 我认为肿瘤性病变可能性大

当然一个图很难说, 但是这种腺体结构加上好多细胞有鞋钉样表现(the cells lining the glands have hobnail appearance) , 要小心透明细胞癌 (clear cell carcinoma).  透明细胞癌的细胞浆也可以是红的eosinophilic cytoplasm.