Acinar pattern of adenocarcinoma composed of glands lined by malignant cells.

幻灯片2.JPG (108.59 KB)

2010-8-10 16:11

Acinar pattern of adenocarcinoma with desmoplastic stroma containing glands with malignant cells exhibiting pleomorphic nuclei.

幻灯片3.JPG (107.6 KB)

2010-8-10 16:11

Cribriform pattern of adenocarcinoma showing small regular round back-to-back glands.

幻灯片4.JPG (127.2 KB)

2010-8-10 16:11

Irregularly shaped invasive glands of adenocarcinoma at periphery of so-called central scar

幻灯片5.JPG (104.62 KB)

2010-8-10 16:11

Solid pattern of adenocarcinoma with a sheet of malignant cells with abundant cytoplasm and scattered mitotic figures lacking gland formation.

幻灯片6.JPG (109.91 KB)

2010-8-10 16:11

Papillary adenocarcinoma with fibrovascular cores surrounded by malignant cells.

幻灯片7.JPG (86.83 KB)

2010-8-10 16:11

Higher power of papillary adenocarcinoma showing atypical vesicular nuclei and prominent nucleoli.

幻灯片8.JPG (123.34 KB)

2010-8-10 16:11

Clear-cell pattern of adenocarcinoma composed of malignant cells with clear cytoplasm.

幻灯片9.JPG (107.48 KB)

2010-8-10 16:11

Sarcomatoid (sarcomatous) pattern of adenocarcinoma composed of spindled cells with elongated pleomorphic nuclei.

幻灯片10.JPG (106.2 KB)

2010-8-10 16:11

Signet-ring pattern of adenocarcinoma with cells containing vacuolated mucin-filled cytoplasm and eccentric nuclei resembling signet rings.

幻灯片11.JPG (75.93 KB)

2010-8-10 16:11

The micropapillary component displays small papillary tufts, which lack a central fibrovascular core ；Gross figure of adenocarcinoma with micropapillary pattern

幻灯片12.JPG (67.89 KB)

2010-8-10 16:11

Small papillary tufts are seen focally in an adenocarcinoma.

幻灯片13.JPG (96.79 KB)

2010-8-10 16:11

A micropapillary pattern can also be observed in the lymphangitic spread of the same tumor.

幻灯片14.JPG (152.69 KB)

2010-8-10 16:11

Fetal Adenocarcinoma. The tumor is characterized by tubules lined by glycogen-rich columnar cells that resemble the fetal lung at 10 to 15 weeks gestational age. Fetal adenocarcinoma, well-differentiated or low-grade variant, appears similar to tfetal lung or endometrial glands, displaying a villiform tubular pattern.

幻灯片15.JPG (142.35 KB)

2010-8-10 16:11

The glandular component of this well-differentiated fetal adenocarcinoma shows two squamoid morules.

幻灯片16.JPG (114.61 KB)

2010-8-10 16:11

On high power, columnar cells in a well-differentiated fetal adenocarcinoma contain glycogen-rich cytoplasm and basally arranged uniform nuclei.

幻灯片17.JPG (130.03 KB)

2010-8-10 16:11

This squamoid morule in a well-differentiated fetal adenocarcinoma consists of ovoid to polygonal cells with ample eosinophilic cytoplasm.

幻灯片18.JPG (113.43 KB)

2010-8-10 16:11

High-grade fetal adenocarcinoma shows glycogen-containing columnar cells with nuclear pleomorphism and prominent nucleoli.

幻灯片19.JPG (105.96 KB)

2010-8-10 16:11

High-grade fetal adenocarcinoma is composed of tubules lined by pleomorphic columnar cells with supranuclear and subnuclear vacuoles.

幻灯片20.JPG (70.51 KB)

2010-8-10 16:11

BAC: defined as adenocarcinoma of the lung that grows in a lepidic fashion along intact alveolar septa without invasion. Wedge resection of nonmucinous BAC showing subpleural tumor with associated subpleural consolidation or so-called scar.

幻灯片21.JPG (75.73 KB)

2010-8-10 16:11

Gross figure of mucinous BAC showing pneumonic tumor spread.

幻灯片22.JPG (134.26 KB)

2010-8-10 16:11

Lepidic growth of nonmucinous BAC along intact alveolar septa

幻灯片23.JPG (112.47 KB)

2010-8-10 16:11

Subpleural nonmucinous BAC showing circumscription and mildly thickened alveolar septa.

幻灯片24.JPG (94.53 KB)

2010-8-10 16:11

Nonmucinous BAC showing cuboidal to columnar cells with focal intranuclear cytoplasmic inclusions.

幻灯片25.JPG (98.55 KB)

2010-8-10 16:11

BAC with cuboidal-to-columnar cells with basally oriented nuclei and eosinophilic or vacuolated cytoplasm proliferating along intact alveolar septa.

幻灯片26.JPG (74.89 KB)

2010-8-10 16:11

Mucinous BAC cells with abundant apical mucin and small basal nuclei lining thin, delicate alveolar septa and projecting into the alveolar spaces as tufts or pseudopapillae.

幻灯片27.JPG (90.97 KB)

2010-8-10 16:11

Mucinous BAC with abundant mucin-rich apical cytoplasm and basally oriented small nuclei growing along thin, delicate alveolar septa.