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1 楼 发表于2010-06-18 11:21:00举报|引用
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Hi, frankbj,
Thank you very much for your interesting case. The GBM appears thickened and stiff, most likely resulting from transplant glomerulopathy. The beautiful C4d stain is helpful, but not required for the diagnosis of transplant glomerulopathy, indicating antibody mediated rejection. In addition, there is intimal thickening with neo-media formation and probable mononuclear cell infiltration. People considers that as active chronic cellular rejection. The photo 6 and 7 show tubulitis, also indicating the component of acute cellular rejection.
The arterial intima also shows myxoid change. I am not sure what it means.
Hi, frankbj,
Thank you very much for your interesting case. The GBM appears thickened and stiff, most likely resulting from transplant glomerulopathy. The beautiful C4d stain is helpful, but not required for the diagnosis of transplant glomerulopathy, indicating antibody mediated rejection. In addition, there is intimal thickening with neo-media formation and probable mononuclear cell infiltration. People considers that as active chronic cellular rejection. The photo 6 and 7 show tubulitis, also indicating the component of acute cellular rejection.
The arterial intima also shows myxoid change. I am not sure what it means.
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