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以下是引用海上明月在2010-6-1 18:05:00的发言: 那是些钙化小体----沙砾体。大体见到肿块和胶冻状物,镜下见到被覆黏液性上皮,其细胞异型性不大,但有一定的异型性。结合27年年前的阑尾切除病史(诊断不详)和当前的形态学改变,考虑原来阑尾黏液性囊腺瘤可能,当前拟诊断为复发性黏液性囊腺瘤,恶性潜能未定。建议多取材观察上皮异型性和组织浸润情况再进一步诊断。 |
It is a very interesting case.
1. The epitheloid strips are most likely reactive mesothelial cells based on the histology and anatomic location. In addition, the pathology of the appendix specimen was unknown. It is extremely rare to have a recurrent appendiceal mucinous neoplasma 27 years later.
2. Agree. The round structures are probably calcification particles. But I would suggest to do silver stain(GMS stain) to rule out remote possiblity of fungal organisms.
3. Is any uninvolved mucosa? Could you provide a couple of photos of the interface of normal mucosa and the ulcerative lesion?
以下是引用谈东风在2010-6-2 22:55:00的发言:
It is a very interesting case.
1. The epitheloid strips are most likely reactive mesothelial cells based on the histology and anatomic location. In addition, the pathology of the appendix specimen was unknown. It is extremely rare to have a recurrent appendiceal mucinous neoplasma 27 years later.
2. Agree. The round structures are probably calcification particles. But I would suggest to do silver stain(GMS stain) to rule out remote possiblity of fungal organisms.
3. Is any uninvolved mucosa? Could you provide a couple of photos of the interface of normal mucosa and the ulcerative lesion? |