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- 右卵巢囊肿,子宫内膜样癌？浆液性癌？
Photos are too dark. It is ovarian serous ca, but not endometrioid ca based on cytomorphology. Most likely it is a high grade tumor. Immunostains are not necessary for this case.
If you want to do some stains to distinguish ovarian high grade serous ca from endometrioid ca, P16, P53 and WT1 are good markers to choose.
More then 80% or 90% ovarian high grade serous carcinomas are positive for p53, p16 and WT1. Most of the endometrioid carcinomas are negative for these markers.
| 以下是引用cqzhao在2010-1-21 10:39:00的发言：
Photos are too dark. It is ovarian serous ca, but not endometrioid ca based on cytomorphology. Most likely it is a high grade tumor. Immunostains are not necessary for this case. If you want to do some stains to distinguish ovarian high grade serous ca from endometrioid ca, P16, P53 and WT1 are good markers to choose. More then 80% or 90% ovarian high grade serous carcinomas are positive for p53, p16 and WT1. Most of the endometrioid carcinomas are negative for these markers. |
照片太暗。据细胞形态其为卵巢的浆液性癌，不是子宫内膜样癌。极有可能是高级别的肿瘤。这一例无需免疫标记。如果想鉴别卵巢高级别浆液性癌与子宫内膜样癌，P16, P53 及 WT1是不错的标记物选择。
超过80%-90%的卵巢高级别浆液性癌p53、p16及WT1阳性。绝大多数的子宫内膜样腺癌这些标记物阴性。
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| 以下是引用cqzhao在2010-1-21 10:39:00的发言：
Photos are too dark. It is ovarian serous ca, but not endometrioid ca based on cytomorphology. Most likely it is a high grade tumor. Immunostains are not necessary for this case. If you want to do some stains to distinguish ovarian high grade serous ca from endometrioid ca, P16, P53 and WT1 are good markers to choose. More then 80% or 90% ovarian high grade serous carcinomas are positive for p53, p16 and WT1. Most of the endometrioid carcinomas are negative for these markers. |
| 以下是引用蔷薇在2011-3-15 16:39:00的发言：
照片太暗。据细胞形态其为卵巢的浆液性癌，不是子宫内膜样癌。极有可能是高级别的肿瘤。这一例无需免疫标记。如果想鉴别卵巢高级别浆液性癌与子宫内膜样癌，P16, P53 及 WT1是不错的标记物选择。 超过80%-90%的卵巢高级别浆液性癌p53、p16及WT1阳性。绝大多数的子宫内膜样腺癌这些标记物阴性。 |
