Some one asked the EIN quiz web. I pasted the Dr. Hecht's email with link here. If you are interested to EIN you can take a quiz. This is dr Hecht's one project. Dealine to the end of September. Every one can join if interested.

Subject: [PATHO-L] EIN-Endometrial Biopsy Tutorial-Quiz

I want to evaluate the reliability of the diagnostic criteria for endometrial pre-cancers; Endometrial Intraepithelial Neoplasia (EIN).

Please review the web-based consensus exercise and take the quiz.

http://flexiform2.unibas.ch/formular.cfm?EID=1760
Endometrial Intraepithelial Neoplasia (EIN) is ready for prime time!
http://flexiform2.unibas.ch/formular.cfm?EID=1760
 
Can you readily identify premalignant endometrial disease?

Adenomatous hyperplasia, Complex atypical hyperplasia or Endometrial Intraepithelial Neoplasia


•       Learn updated diagnostic criteria using a web based training module
•       Participate in an exercise to demonstrate diagnostic reproducibility
•       Test your diagnostic skill on cases from community practice and
•       See how you compare to your colleagues

Your participation is anonymous, but we ask that you

1.      Only take the consensus quiz once
2.      Complete the quiz (don’t just answer randomly to see the explanations)

http://flexiform2.unibas.ch/formular.cfm?EID=1760

If you would like an explanation for the answers without participating in the quiz, please contact Dr. Hecht  at:  JLHecht@bidmc.harvard.edu

Sponsored by:
Dr. Jonathan L. Hecht - Harvard Medical School , USA Dr. Vinita Parkash - Yale University School of Medicine, USA Dr. Katharina Glatz - Universitaetsspital Basel, Switzerland

Also you can get in this web http://www.endometrium.org/ to know the EIN.

We do not use EIN system. So I am not very familiar with it. If you use the term in your practice or if you are interested to EIN, these web or links are very good to know the basic knowledge.

One week late some one can help put the topic in Gyn section only.

Thanks,

cz

 哈哈，估计楚尔.豪森上世纪八十年代说：“HPV是宫颈癌的元凶的时候”；估计全世界没有几个人相信他。但是等到去年的时候，诺贝尔奖颁发给他的时候；全世界都认可了他。其实任何事物我们都要辨证的看待和分析。

1、现在几乎所有的病理学家都认可了CIN；但是EIN还没有被大多数接受。

2、说明了目前的水平下EIN诊断的复杂性和不可预知性——这也是其诊断的挑战性。

3、EIN是否能成为诊断宫内膜癌的癌前病变需要很多研究数据来支持。

4、我希望我们中国的病理学家或细胞学家不光拿经验说话也要拿数据证实自己的论断。

 谢谢赵老师, 

 想了解学习EIN，还可以去网站www.endomtrium.org。虽然关于EIN的概念提出已经近十年，但是至今并未推广应用，原因是多方面的，EIN概念的提出是基于计算机辅助的形态测量、分子生物学检测（如克隆性分析）等，实际应用受到局限。EIN的倡导者正试图依据HE和IHC，简化EIN的诊断。不管目前采纳与否，至少应该了解这一概念。

有位大专家说：EIN相当于重度非典型增生。实际上是断章取义，并未真正理解EIN的概念。