This is most likely a WHO grade II ependymoma of cerebellum, but I would like to see higher power views of cells in Figures 4-6 to appreciate the cytologic and nuclear details. Other than perivascular pseudorosettes in Figures 4-5, it there any formed ependymal canal? Please show the GFAP stain and do EMA stain if possible. Thanks.

 

图1-2：稀疏区高倍 X40

图2-3：高密度区高倍 X40

图5：中等密度区高倍 X40

图6-7：GFAP（＋）

EMA（－）

衷心感谢马教授指导和帮助！

 好好跟马教授学习。

 同意马老师的意见，诊断为室管膜瘤（WHO 2级），尽管灶性区域有坏死，但细胞无间变，未见核分裂，不能诊断为间变性室管膜瘤。

The hypocellular areas suggest subependymoma, but the overall features are that of a WHO grade II ependymoma. 

 图片很漂亮，学习了！

 学习了！

   图片很漂亮，学习

 不知马老师有没有典型的formed ependymal canal图片给大家欣赏啊？