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lantian0508 离线
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stevenshen 离线
There are a number of ways to issue the repot. If you agree and SURE that a tumor indeed has features of oncocytoma and chromophobe RCC. My suggestion would be either "Chromophobe RCC (eosinophilic) with focal oncocytoma feature" or "unclassified oncocytic RCC" and write a note or comment at the end of your report. If you are not an expert and don't have too much experience with renal tumor, it is a good idea to get a consultation. Oncocytoma is a benign tumor; fortunately eosinophilic chromophobe RCC is a low grade tumor; the treatment is the same. The risk for underdiagnosis of a true carcinoma is that you will be embrassed or in trouble if patient develop recurrence or metastasis in the future. I hope this is helpful. 回复仅供参考
stevenshen 离线
lantian0508 离线
lantian0508 离线
唐平老师关于嫌色细胞癌的文章:
瘤体较大,常单个,境界明显,坏死出血少见,包膜完整很少突破肾包膜。光镜下肿瘤细胞呈腺泡状排列,细胞大,胞浆丰富,常见两种类型细胞,胞浆淡染呈细网状甚至透明的气球样的I型细胞及胞浆嗜酸性呈细颗粒状的Ⅱ型细胞。这两种类型的肿瘤细胞的PAS和苏丹Ⅳ染色均显示其胞浆内缺乏糖原和脂滴。Hale胶体铁染色,胞浆阳性,呈亮蓝色,说明肿瘤细胞含有酸性粘液物质。免疫组织化学染色Vimentin阴性,CK8、CK7、CK19阳性,CK20阴性。电镜下见胞浆内大量的小空泡,二型细胞均可见。小空泡的存在是嫌色细胞癌区别于其它肾肿瘤的独特之处,亦是光镜下其独特细网状胞浆的结构基础。