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名称: | |
描述: | |
姓 名: | ××× | 性别: | 年龄: | 82 | |
标本名称: | 外阴 | ||||
简要病史: | 发现 赘生物3个月 | ||||
肉眼检查: |
Guide for signing out VIN cases according to new ISSVD Classification:
Histology |
Final Diagnosis |
Comment |
VIN-1 |
SQUAMOUS EPITHELIUM WITH ATYPIA, CONSISTENT WITH HPV-RELATED CHANGES |
The above lesion is equivalent to vulvar intra-epithelial neoplasia 1(VIN-1) lesion according to the old classification scheme. The new International Society for the Study of Vulvovaginal Disease (ISSVD) classification no longer includes “VIN-1” as a type of VIN. This is due to lack of evidence that “VIN-1” is a cancer precursor lesion. References: J Low Genit Tract Dis. 2007;11:46-47. J Reprod Med. 2005;50:807-10. |
VIN-2 or VIN-3 |
VULVAR INTRAEPITHELIAL NEOPLASIA (VIN), USUAL WARTY TYPE.
VULVAR INTRAEPITHELIAL NEOPLASIA (VIN), USUAL BASALOID TYPE.
VULVAR INTRAEPITHELIAL NEOPLASIA (VIN), USUAL MIXED (WARTY/BASALOID) TYPE. |
The above diagnosis is based on the new International Society for the Study of Vulvovaginal Disease (ISSVD) classification of vulvar intra-epithelial neoplasia (VIN). The above lesion is equivalent to VIN-2 (or VIN-3) according to the old classification scheme. Reference: J Low Genit Tract Dis. 2007;11:46-47. |
VIN-differentiated type |
VULVAR INTRAEPITHELIAL NEOPLASIA (VIN), DIFFERENTIATED TYPE. |
The above diagnosis is based on the new International Society for the Study of Vulvovaginal Disease (ISSVD) classification of vulvar intra-epithelial neoplasia (VIN). The risk of progression to invasion seems greater in differentiated VIN than in usual VIN. References: J Low Genit Tract Dis. 2007;11:46-47. Int J Gynecol Pathol. 2001;20:16-30. |