| 图片： | |
|---|---|
| 名称： | |
| 描述： | |
- B516外阴赘生物
图1
图2
图3
图4
图5
图6
图7
图8
图9
图10
图11
图12
图13
| 姓 名： | ××× | 性别： | 年龄： | 82 | |
| 标本名称： | 外阴 | ||||
| 简要病史： | 发现 赘生物3个月 | ||||
| 肉眼检查： | |||||
标签：外阴 尖锐湿疣
-
本帖最后由 于 2007-08-17 15:54:00 编辑
相关帖子
- • GYN Case 3 from USCAP 2007
- • 外阴肿物
- • 外阴疣状物
- • 外阴肿块
- • 外阴肿块
- • 欣赏-外阴病变
- • 外阴结节
- • 搞笑病例2__妇科专家不知道外阴派杰病？
- • 外阴粘液性肿物
- • 外阴大肿块
×参考诊断
尖锐湿疣（鉴别疣状癌）
-
本帖最后由 于 2009-06-11 05:23:00 编辑
Above is new classification. Condyloma is type of VIN 1. Now diagnosis of VIN1:
SQUAMOUS EPITHELIUM WITH ATYPIA, CONSISTENT WITH HPV-RELATED CHANGES
HPV infection rate is 77% for VIN1 with only 14% HPV 16/18.
HPV infection rate is 77% for VIN1 with only 14% HPV 16/18.
Do we know HPV type for this 82 year-old lady?
Guide for signing out VIN cases according to new ISSVD Classification:
|
Histology |
Final Diagnosis |
Comment |
|
VIN-1 |
SQUAMOUS EPITHELIUM WITH ATYPIA, CONSISTENT WITH HPV-RELATED CHANGES |
The above lesion is equivalent to vulvar intra-epithelial neoplasia 1(VIN-1) lesion according to the old classification scheme. The new International Society for the Study of Vulvovaginal Disease (ISSVD) classification no longer includes “VIN-1” as a type of VIN. This is due to lack of evidence that “VIN-1” is a cancer precursor lesion. References: J Low Genit Tract Dis. 2007;11:46-47. J Reprod Med. 2005;50:807-10. |
|
VIN-2 or VIN-3 |
VULVAR INTRAEPITHELIAL NEOPLASIA (VIN), USUAL WARTY TYPE.
VULVAR INTRAEPITHELIAL NEOPLASIA (VIN), USUAL BASALOID TYPE.
VULVAR INTRAEPITHELIAL NEOPLASIA (VIN), USUAL MIXED (WARTY/BASALOID) TYPE. |
The above diagnosis is based on the new International Society for the Study of Vulvovaginal Disease (ISSVD) classification of vulvar intra-epithelial neoplasia (VIN). The above lesion is equivalent to VIN-2 (or VIN-3) according to the old classification scheme. Reference: J Low Genit Tract Dis. 2007;11:46-47. |
|
VIN-differentiated type |
VULVAR INTRAEPITHELIAL NEOPLASIA (VIN), DIFFERENTIATED TYPE. |
The above diagnosis is based on the new International Society for the Study of Vulvovaginal Disease (ISSVD) classification of vulvar intra-epithelial neoplasia (VIN). The risk of progression to invasion seems greater in differentiated VIN than in usual VIN. References: J Low Genit Tract Dis. 2007;11:46-47. Int J Gynecol Pathol. 2001;20:16-30. |
| 以下是引用shihuaiy 在2007-1-30 22:33:00的发言：
外阴疣状肿瘤以湿疣状癌（condylomatous carcinoma）相对较多，疣状癌（verrucous carcinoma）次之，巨大或增生性尖锐湿疣外阴少见。湿疣状癌和疣状癌的区别在于后者异型性较小，HPV以6型多见，乳头中间质不明显。此例有异型性和较多的核分裂像，乳头间质明显，有挖空样细胞，考虑为湿疣样癌（HPV16多见）可能性较大。文献报道该肿瘤预后很好，可以复发但转移少见。等待学习！ |
-
Sorry for missing Professor Zhou's teaching on this case and I have no idea what the final diagnosis of Dr. Zhou provides. My two penny personal opinion is a "Warty type of squamous carcinoma" in this 82 year old lady. I do not think this is a verrucous carcinoma due to less impressive "bulky and pushing base" which is vanishingly rare. Also it is way beyond of condyloma cytologically. You have to think three times before to make a diagnosis of condyloma in a 82 year old lady socioeconomically. I am humblely listening to Professor Zhou's comment and critiques here. Thanks you.
- 不坠青云之志，长怀赤子之心
外阴疣状肿瘤以湿疣状癌（condylomatous carcinoma）相对较多，疣状癌（verrucous carcinoma）次之，巨大或增生性尖锐湿疣外阴少见。湿疣状癌和疣状癌的区别在于后者异型性较小，HPV以6型多见，乳头中间质不明显。此例有异型性和较多的核分裂像，乳头间质明显，有挖空样细胞，考虑为湿疣样癌（HPV16多见）可能性较大。文献报道该肿瘤预后很好，可以复发但转移少见。等待学习！
- the more we discuss, the more we learn from each other !!
