以下是引用tumor 在2006-12-11 20:52:00的发言：
从此例典型的脊索样特点加上病人临床特征，首先考虑的是第三脑室脊索样胶质瘤，与发生于该部位的毛星、垂体腺瘤以及颅咽管瘤容易鉴别，但从图2中淋巴浆细胞形成淋巴滤泡生发中心来看，极似脊索样脑膜瘤特征，做个GFAP极可鉴别，后者阴性。 |
Indeed this is a classic case of chordoid glioma of the third ventricle, a recently described entity. Its histopathology and anatomic location are both vert characteristic. The tumor is always solid, circumscribed and contrast-enhancing. Microscopically, the epithelioid and fairly uniform neoplastic cells have small or medium sized oval central nuclei and plump eosinophilic, GFAP-positive cytoplasm. They often form cords between myxoid or fibrillary substance infiltrated focally by lymphoplasmacytic cells. Vague cellular nodules may be present. Some cells may be EMA-positive. Mitotic figures could be found, but necrosis or vascular proliferation is not seen. The differential diagnoses include chordoid meningioma, chordoma, chordoid chondrosarcoma, gangliocytoma and gemistocytic astrocytoma. It is considered a low grade tumor (provisionally WHO grade II) that does not recur after total resection. Residual tumor after partial resection is either stable or grows slowly. Great case this is!
