似前列腺基底细胞增生伴鳞化,但要除外基底细胞癌和内翻生长型的低级别尿路上皮癌伴鳞状分化.

 不太像癌,,部分向鳞癌分化

 不太像癌,,部分向鳞癌分化

 不太像癌,,部分向鳞癌分化

 有无化生性鳞癌说法？

 同意4楼高见。不太像癌。鳞状上皮完全良性。腺上皮也还好，只是结构比较紊乱。

 前列腺腺癌，部分向鳞癌分化。

Interesting but difficult case to interpret...I favor it to be non-neoplatic.  It most likely represent florid basal cell hyperplasia and extensive squamous metaplasia.  It is not typical of prostate adenocarcinoma.  Other considerations include prostatic transitional cell carcinoma with squamous differentiation or primary prostate squamous cell carcinoma, both of which are exceedingly rare. Some areas superficially resemble ductal endometriod-like prostate carcinoma, but don't think it is.  Looking forward to hear other expert's opinion and patient follow-up from the submitting pathologist if available. Thanks!

 ?