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jiangxiaoyu 离线
Looks like LSIL including HPV effect, but not sure, because i don't see good reference cells in the field. You need reference normal intermediate cells to judge nuclear size and darkness. You need nuclear size >3X the size of intermediate cell nuclei and darker chromatin, plus nuclear membrane irregularity. Perinuclear halo is not sufficient without nuclear abnormality and is not necessary for LSIL.
Please remember: when you diagnose LSIL, you also have diagnosed HPV infection. LSIL is caused by HPV infection.
Sorry. Didn't notice it is an old case.
以下是引用mingfuyu在2008-11-27 9:47:00的发言: Looks like LSIL including HPV effect, but not sure, because i don't see good reference cells in the field. You need reference normal intermediate cells to judge nuclear size and darkness. You need nuclear size >3X the size of intermediate cell nuclei and darker chromatin, plus nuclear membrane irregularity. Perinuclear halo is not sufficient without nuclear abnormality and is not necessary for LSIL. Please remember: when you diagnose LSIL, you also have diagnosed HPV infection. LSIL is caused by HPV infection. Sorry. Didn't notice it is an old case. |
译文(新手上路 请多指点):
疑似低级别鳞状上皮内病变(LSIL).由于视野中没有形态良好的中层细胞作为参照,故不能确诊。
在诊断LSIL的时候需要参照中间层细胞,以判断核的大小和染色的深浅。诊断LSIL需满足如下几点:核增大并超过正常中层细胞核3倍、核染色质深染、核膜不规则。仅有核周空晕而无核改变者不足以诊断LSIL,并且核周空晕也并非确诊LISL必需。
请记住:由于LSIL是由HPV感染所造成的,所以在做出LSIL诊断的同时也诊断了HPV感染的存在。
wolflovepig 离线