发表于 2008-3-15 21:25 {
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- zcyonze脑肿瘤
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From first couple of pictures in low power fields, prominent vascular proliferation can be seen. On high power field, nuclear pleomorphism can be seen, I think this is a high grade glioma, favor GBM. This patient is 73 years old, he is too old for ependymoma.
Meningioma is a good thought, but I didnot see the cellular wholes. Please consult the MRI film. Again, when you call malignant meningioma, the mitoses count needs to be higher than 20/10 HPF. this is the single and the most important dx criteria.
I hope this may be helpful.
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本帖最后由 于 2008-04-04 10:23:00 编辑
我觉得有点室管膜瘤的味儿
管理员声明：补充Dr.fyshan3月17日的跟贴意见（“for some reason, I cannot submit my comment on line. my comment is as following”）：
MRI showed enhancing mass lesion, which is the characteristic features of high-grade gliomas. Although some cells with clear cytoplasm, the nuclei features favor astrocytic origin. Based on the first couple photos with vascular proliferation, as well as high Ki-67 index, I favor the diagnosis of GBM, glioblastoma multiform (WHO IV)
PXA (Pleomorphic xanthoastrocytoma) is a young patient's lesion, MRI usually shows cystic lesion with intramural nodule. Histologically, more pleomorphic, usually with giant cells, calcification and eosinophilic granular bodies, Rosenthal fibers. No or rare mitosis, no necrosis. Ki-67 should be lower than 1%.
朱正龙
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| 以下是引用fyshan在2008-3-29 1:17:00的发言： From first couple of pictures in low power fields, prominent vascular proliferation can be seen. On high power field, nuclear pleomorphism can be seen, I think this is a high grade glioma, favor GBM. This patient is 73 years old, he is too old for ependymoma. |
朱正龙
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