孔祥田(Max)*Sacramento*CA] 02-26 03:55

A consult case: 60ish M TURP. Your Dx?

孔祥田(Max)*Sacramento*CA] 02-26 03:55

孔祥田(Max)*Sacramento*CA] 02-26 03:55

孔祥田(Max)*Sacramento*CA] 02-26 03:55

孔祥田(Max)*Sacramento*CA] 02-26 03:55

孔祥田(Max)*Sacramento*CA] 02-26 03:55

孔祥田(Max)*Sacramento*CA] 02-26 03:55

孔祥田(Max)*Sacramento*CA] 02-26 04:10

艾迪利（赵某） 02-26 07:57

pax2?

郑州大学第二附属医院~胡桂明 02-26 08:23

病变由增生的小管状腺体组成，有些含嗜酸性分泌物，被覆扁平或立方上皮，有些柱状上皮可能是电损伤后便核变长？有靴钉样细胞。间质水肿，炎细胞浸润。符合肾源性腺瘤/化生。可能发生在前列腺尿道部。

郑州大学第二附属医院~胡桂明 02-26 08:26

主要鉴别诊断是中肾残余，后者一般无间质反应，腔内含稠密的嗜酸性物质。

郑州市中心医院张全武 02-26 08:28

同意肾源性化生@郑州大学第二附属医院~胡桂明 

郑州市中心医院张全武 02-26 08:28

同意肾源性化生@郑州大学第二附属医院~胡桂明

孔祥田(Max)*Sacramento*CA] 02-26 11:39

孔祥田(Max)*Sacramento*CA] 02-26 11:39

孔祥田(Max)*Sacramento*CA] 02-26 11:40

孔祥田(Max)*Sacramento*CA] 02-26 11:46

Yes. It’s metanephric adenoma(NA)/metaplasia. The submitting pathologist thought adenocarcinoma based on prostate triple stains. I added pax8 and PSA+PAP. If you look carefully, there is scant urothelium near the lesion indicating this is from prostatic urethra. Prostatic adenocarcinoma is in the ddx but cannot be positive for pax8. NA can be negative for prostate basal cell markers and positive for AMACR which really a misleading to be easily misdiagnosed as prostatic adenocarcinoma. You guys did a great job on this case! Thanks for your comments!

孔祥田(Max)*Sacramento*CA] 02-26 15:46

nephrogenic adenoma/metaplasia. There is typo above!

郑州市中心医院张全武 02-26 15:48

@孔祥田(Max)*Sacramento*CA]

郑州大学第二附属医院~胡桂明 02-26 18:37

谢谢@孔祥田(Max)*Sacramento*CA] 老师

慧馨 03-01 18:01

慧馨 03-01 18:01

慧馨 03-01 18:01

慧馨 03-01 18:01