Thanks for your all input. This is a tough case. It is a partial atrophy.

Partial atrophy is the most common mimicker of prostate adenocarcinoma. Partial atrophy has a certin amount of cytoplsm, which is normally pale stained. It can have infiltrative pattern. Partial atrophic glands have infolding in the lumen. You can see small nucleoli, not like the one in cancer-large melanoma-like eosinophilic nucleoli. When you performe immunostain, partial atrophy normally have at least partchy basal cell stain. However, it is not uncommon you can see negative basl call stain. We see those suspicious stain almost everyday. Partial atrophy can be positive for AMACR. When you have partial atrophy with negative basal stain and positive AMACR, which is a cancer pattern, it is very confusing. Please pay attention to this mimicker.

I just want to bring you attention to it so that nobody make a mistake to make a benign partial atrophy as cancer.