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kangjinghua 离线
性别 | 男 | 年龄 | 70 | 临床诊断 | |
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一般病史 | 排尿困难 | ||||
标本名称 | 无 | ||||
大体所见 | 无 |
图1图2有三个小腺体没有肌上皮,但是高分子CK也有点弱阳,而图1与图5是相对应的,图5的肌上皮阴性,但是504s也是阴性。中间几幅图的腺体边上有一两个基底细胞,算阳性。图10开始有几个腺体周围肌上皮完全缺失(CK34E12也阴性,没采图)。这种腺体完整没有基底细胞到底是真没有还是只是部分缺失了?这几个小腺体HE腺腔中有的有深红染杆状分泌物。除了这几个腺体,其它所有玻片的腺体都比较典型的良性增生改变,就是这几个腺体稍微有点疑问?谢谢指点
可能是某种原因造成基底细胞缺失,不像肿瘤性。
The differentiation of small foci of prostatic carcinoma seen in core biopsies from mimics may be problematic. The process of performing the biopsy may distort the tissue. Both carcinoma and its mimics may be composed of small glands.
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prostatic hypertrophy | scattered glands may be negative | positive in some cases | positive | |
atypical adenomatous hyperplasia | variable proportion of glands may be negative | positive in some cases | positive | |
flat high-grade PIN | staining may be fragmentary | positive in more than 50% of cases | positive | |
prostatic intraduct carcinoma | basal cells may be present |
| positive | |
basal cell hyperplasia | basal cells positive | negative | positive | |
atypical basal cell hyperplasia | basal cells positive | negative | positive | |
seminal vesicles | basal cells positive | negative | ||
ejaculatory duct epithelium | basal cells positive | negative | negative | |
nephrogenic adenoma | may be completely negative for basal cell markers | variable | negative/ weakly positive | |
benign mesonephric remnants | may be completely negative for basal cell markers | ? | negative | |
Cowper's glands | variable | ? | variable | |
Prostatic adenocarcinoma | Positivity may be seen in high grade carcinomas, but is luminal. Positivity is rarely seen in gland-forming acinar carcinomas (Gleason grades 2 to 6). | positive, except variants such as foamy cell, atrophic and pseudohyperplastic. | positive | |
min wang