间变型少突星形胶质细胞瘤，3级。建议免疫组化：GFAP，Olig-2，KI-67等

 间变型少突胶质细胞瘤？

免疫组化：GFAP、S-100，Vimentin，Olig-2，KI-67。

 This is a high grade glioma, consistent with grae 4 GBM. Please pay attention on the last picture showing the tumor nuclei is more

astroctyic than oligodendrocytic. Pic 4 with necrosis. focal calcification may indicate the tumor is from a low-grade progress to high grade.

 星形细胞瘤，2级。