2图，怎么诊断

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What we learn from this case?

AGC is a very difficult diagnosis. About 20% AGC can have significant lesions including squamous lesions, endocervical lesions and endometrial leasions. In other words, most of AGC cases are benign. We have to be very cautious to make dx of AGC on Pap. Clinical information, age, previous Pap, HPV results et al should be considered.

In hypercellular specimen if you think it may be a malignant case you can try a cell block. It may be helpful.

It is difficult to evaluate AGC origin on Pap. It is often difficult in cervical biopsy specimen. Please do not need to commit your self.

High risk HPV testing may be helpful for assessment of risk for AGC women. The chance od high grade lesions (squamous and cervical glandular) is very low in women with AGC and negative HPV testing. Of cause HPV infection has no relation to endometrial carcinoma.

The most importance we should remember is that Pap test is screening test.

Ok, I finish my case and hope your guys like the case.

Thank all people who read or joined in the discussion for this case

The residual fluid of the Pap was prepared for  a cell block. How will you release your Pap test now?

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名称：图2
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