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性别 | 男 | 年龄 | 57岁 | 临床诊断 | - |
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一般病史 | 发现左侧乳头、乳晕破溃,流脓3年 | ||||
标本名称 | 左乳 | ||||
大体所见 | 灰白色组织一块,大小4×1.8cm,表面见一大小2×1.2cm灰白色肿物。 |
太靠近皮肤,建议考虑汗腺起源的癌,Paget病一般HER2强阳性,本例不符合
rosens breast pathology第三版上有这样一句话:The expression of estrogen and progesterone receptors in sweat gland carcinomas and breast carcinomas was not significantly different. Hanby et al. (37) studied 12 examples of primary mucinous carcinoma of the skin and found all of the tumors to be strongly immunoreactive for estrogen receptor. Progesterone receptor was also detected in the 12 tumors, but staining was heterogeneous and weak in some instances.