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- 上消化道出血
Whipple's disease is a rare systemic infection due to Tropheryma whippelii, a gram positive intracellular actinomycete (World J Gastroenterol 2009;15:2078), first described in 1907 by Dr. George Hoyt Whipple. Dr. Whipple won the Nobel Prize (jointly) in 1934 for another discovery, that liver given as food to dogs reversed the anemia, leading to treatment of pernicious anemia. He was friends of Dr. Allen Whipple, a surgeon who described the Whipple procedure and the Whipple's triad of insulinoma.
