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性别 | 女 | 年龄 | 13 | 临床诊断 | 卵巢肿瘤 |
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一般病史 | 卵巢肿瘤 | ||||
标本名称 | 左卵巢肿块。 | ||||
大体所见 | 冰余左卵巢囊肿10*3*2,囊壁样,厚0.2-1cm,另送左卵巢20*15*6cm,囊性,厚约0.3cm,切面灰白淡红,质软。 |
hematoxylin 离线
形态学结合临床,那还是首先考虑 Sertoli-Leydig瘤。
Sertoli细胞,即 支持细胞,分布在正常发育的睾丸曲精小管,是支持精原细胞发育至成熟精子的“支架”和辅助发育“设施”细胞。
Leydig细胞,即 睾丸间质细胞,是分泌雄激素的细胞,从而促进睾丸发育成熟、精子发育成熟,促进男性的第二性征发育,维持男性第二性征。
xiaofeng1008 离线
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Cord-like structure: sertoli cells
Clusters of pink cells: leydig cells
So It should be sertoli leydig cell tumor.
However, we generally do some stains for these kinds of cases, such as inhibin, calretinin.
WT1 stains sertoli cells, but not leydig cells
These are mucinous glands.
Overall I think the diagnosis is sertoli leydig cell tumor with heterologous elements.
About 20% of SLCTs have the heterologous elements. Most of the SLCT with heterologous elements are intermediate differentiated. Gastric or intestinal type of epithelium lined glands or cysts are the most common heterologous elements. Others like foci of carcinoid, cartilage, et al can occur also.
北京会诊考虑为sertoli-leydig 瘤伴粘液性囊腺瘤,小区为交界性。继续会诊中。
伴粘液性囊腺瘤,小区为交界性. Not sure the diagnosis.
I think the diagnosis "sertoli leydig cell tumor with heterologous elements" is more appropriate.
The internet speed is too slow. I spent 45 minutes for this case. I feel terriable and disappointed.
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