Clinical Signs
l 1.
Radiographically identifiable periosteal mass.
l 2.
Palpable mass adjacent to small bones in the hands or foot.
l 3.
Pain in the region of a periosteal mass.
Microscopic
l 1.
The lesional tissue is composed of bone, cartilage, and fibrovascular connective tissue.
l 2.
The cartilage tends to be less well organized than is the case in osteochondromata.
l 3.
The endochondral ossification present in the lesional tissue tends to be less well organized than in osteochondromata.
l 4.
The spindle cell component of the lesion may show some mitotic activity, but no atypia is evident.
l 5.
A distinctive feature of BPOP is the presence of irregular calcified matrix, which stains blue (hematoxylin and eosin) and has been referred to as “blue bone.”
l 6.
The lesion is very well circumscribed at the periphery.
Clinical Signs
l 1.
Radiographically identifiable periosteal mass.
l 2.
Palpable mass adjacent to small bones in the hands or foot.
l 3.
Pain in the region of a periosteal mass.
Microscopic
l 1.
The lesional tissue is composed of bone, cartilage, and fibrovascular connective tissue.
l 2.
The cartilage tends to be less well organized than is the case in osteochondromata.
l 3.
The endochondral ossification present in the lesional tissue tends to be less well organized than in osteochondromata.
l 4.
The spindle cell component of the lesion may show some mitotic activity, but no atypia is evident.
l 5.
A distinctive feature of BPOP is the presence of irregular calcified matrix, which stains blue (hematoxylin and eosin) and has been referred to as “blue bone.”
l 6.
The lesion is very well circumscribed at the periphery.