患者女性，29岁，左肾上级囊性肿物，直径4.5cm。

此例最终诊断为：（左侧）多房性囊性肾细胞癌（MCRCC），也叫多囊性透明细胞肾细胞癌（RCC）和多囊性肾细胞癌；

 免疫组化结果是：AE1/AE3(3+)，CD68(-)，Vimentin(-)，CD10(+)，RCC(+)，Ki-67(+2%)

（1）MCRCC是一种预后极佳的少见的肾脏囊性肿瘤；2004年WHO肾肿瘤分类中将MCRCC作为透明细胞肾细胞癌的一种罕见亚型，其预后极佳。

（2）肿瘤直径1-14cm，平均4.9cm，68%的肿瘤Fuhrman分级多为Ⅰ级；5年生存率约100%；

（3）MCRCC应与多囊肾、节段性囊性疾病、囊性肾瘤和其他囊性肾细胞癌鉴别；

（4）近年来有作者建议应将MCRCC从新命名和分类，以提示该肿瘤大多数为良性。推荐使用低度恶性潜能的多囊性肾细胞癌作为这个病变的合适名称。

囊性肾透明细胞癌

是不是透明细胞癌啊？期待结果

 上传部分免疫组化结果

支持一楼

囊性透明细胞型肾细胞癌。

单纯性囊肿伴组织细胞反应 还是囊肿伴发透明细胞癌 

标记CD10  和 CD68  应该可以鉴别吧

期待答案

DX: Multilocular cystic renal cell carcinoma

1.The cysts are usually lined by a single layer of epithelial cells or lack an epithelial lining. The lining cells may be flat or plump and their cytoplasm ranges from clear to pale. Occasionally, the lining consists of several layers of cells or a few small papillae are present .The nuclei almost always are small, spherical,and have dense chromatin.
 2. The septa consist of fibrous tissue, often densely collagenous. Within some of the septa there is a population of epithelial cells with clear cytoplasm. The epithelialcells resemble those lining the cysts and almost always have small dark nuclei.The clear cells form small collections but do not form expansile nodules. These epithelial cells often closely resemble histiocytes, or lymphocytes surrounded by retraction artefacts. Increased vascularity within the cell clusters is a clue to their nature.

 多房性囊性肾癌，经典病例。

可以标记CA IX，CAIX是透明细胞癌更好的标记物。

 囊性透明细胞型肾细胞癌，图2组化是啥，看不了

肾单纯囊肿