到北京一家大医院会诊，诊断为“乳腺囊肿病”，主要理由是CK5/6局灶阳性.

Nonsense.

CK5/6 stain no any meaning in this case

小叶原位癌

It is a very easy case. E-cad stain to confirm the nature of the lesion and Myoepithelial stain to confirm if the invasion is present or not.

There is no any reason for the consultation hospitals to make wrong diagnosis for this case

Maybe Henan

Really in henan

苦恼的是，因两家上级医院专家的会诊意见，而导致的医患纠纷，我们却无言可对。

If you are primary pathologist and think you are right, just persist your dx regardless of the 上级医院or 专家.

感谢赵老师教诲！

呵呵

大医院也有“高级”糊涂虫啊。

 其实本例的肿块组织像是挺多样性的，上传部分区域请大家讨论。

 上传会诊单位免疫组化图片，请大家评判。

支持楼主的诊断

小叶上皮内瘤变

支持小叶内瘤变，感觉CK5/6标记的还是基底细胞，而不是马赛克样的阳性。

LCIS，HER-2的检测似乎在ADH和CIS中没有意义。

结合形态和免疫组化，符合小叶原位癌。

支持小叶内瘤变