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Normal tissue from seminal vesicle, ejaculatory duct, Cowper's glands, and paraganglia can be found incidentally in prostatic resection specimens and lead to diagnostic errors.[150,169,178,184,186] This is particularly true for the seminal vesicle because of its complex papillary arrangement and sometimes striking nuclear aberrations (Fig. 18.7). A clue to the nature of this epithelium is the presence of abundant lipofuscin granules in the cytoplasm.[170] It should be noted, however, that a similar pigment can be occasionally found in benign and malignant prostatic epithelium,[135] and that the distal seminal vesicle epithelium may show some immunoreactivity for PSA. Another clue is provided by the immunoreactivity of the seminal vesicle–ejaculatory duct epithelium for MUC6.[171]
Fig. 18.7 |
虽然图18.7是一个前列腺细针穿刺活检中出现精囊上皮的图,但是正文第一句话提出来精囊、射精管、尿道球腺、副神经节可以偶然的出现在前列腺切除术标本中,容易导致诊断错误。
Bladder: 膀胱
Seminal vesicle: 精囊
Ejaculatory duct: 射精管
Rectum: 直肠
Distal urethra: 远端输尿管
Anterior fibromuscular stroma: 前肌纤维基质
Proximal urethra: 近端输尿管
Periurethral zone: 尿道周围区
CZ(Central zone): 中央区
TZ(transitional zone): 移行区
PZ(peripheral zone): 周围区