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孕14W;胎儿停止发育;引产;
liguoxia71 离线
Pathologic examination of intrauterine fetal death is complicated and should include the following:
1. Maternal history, including results of previous pregnancies, any significant family history, and particular abnormal course in this pregnancy
2. Placenta needs to be examined carefully, especially for signs of congenital infections, thrombosis and vasculopathy
3. Fetus examination should emphasize gross examination more than microscopic examination. Confirm maceration of fetal surface. Determine gestational age by measurements (especially foot length), and carefully exclude anomalies on external appearance as well as internal organs. Most of the time, tissues/organs are autolyzed and microscopic examination yields little useful information.
4. Cytogenetic analysis (karyotyping) of the most viable fetal tissue (placenta and/or skin) may help identify or confirm genetic abnormalities and prognosticate risk for recurrence of abortion in future pregnancy
This is a highly specialized field, and experience helps a lot. Unfortunately, few general pathologists can accumulate sufficient experience in this type of specimens in their practice.
聞道有先後,術業有專攻