Breast core biopsy

Fig 1 10x Fig 2 20x, fig 3 40x

Fig 4 another area 20x

Fig 5 40x  same area as fig 4

It is invasive ductal carcinoma with apocrine feature and also cytoplasmic mucin production.

It is a rare case. Bottomly it is invasive ductal carcinoma.

Singet ring ductal carcinoma??

thanks

 Will you diagnose invasive lobular ca or invasive  ductal ca?

 mucicarmin stain

 P120 stain

 E-cad stain

The patient has no any history of cancers. ER and PR (not shown) are strongly and diffusely positive.

Metastatic tumor is excluded basically. It is a breast carcinoma.

What type?

ER stain result

Why do you think it is lobular ca? Are you sure?

Pan Cytokeratin stain is strongly and diffusely positive. Clearly some differential diagnoses can be excluded.

What are your DDXs now

Above analysis is very reasonable

This is stain of AE1/AE3

Above photos represent the entire lesion in the core biopsy specimen.

Your diagnosis and differential diagnosis?

Thanks