先附上《妇产科诊断病理学》2007版的内容
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下面是2009版的内容
Dysgerminoma cells contain abundant intracytoplasmic glycogen that can be highlighted by PAS that disappears with diastase digestion. The cells typically show strong cytoplasmic membrane staining for PLAP. Recently, c-kit (CD117) and OCT4 positivity (Figure 13.7) has been reported in up to 92% and 100% of dysgerminomas respectively. Tumor cells are frequently positive for vimentin, LDH, and neuron-specifi c enolase (NSE). Approximately 30% of dysgerminomas contain scattered cells positive for cytokeratin. They are negative for EMA, CEA, S-100 protein, leukocyte common antigen (LCA), and AFP. Syncytiotrophoblast cells stain for β-hCG.
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本例表达PLAP、CD117,考虑为无性细胞瘤,浸润淋巴细胞为T细胞,CD20未见阳性表达,支持诊断,子宫腔内外各见一肿瘤,考虑转移可能性大,但患者术后失访,不清楚卵巢及其他可能发生此肿瘤的组织器官检查情况。原单位最初诊断为透明细胞癌,未考虑到此病的可能性,且不具备免疫组织化学检查技术条件,导致此例是原发还是转移成为一个悬案。
先附上《妇产科诊断病理学》2007版的内容
---------------------------------
下面是2009版的内容
Dysgerminoma cells contain abundant intracytoplasmic glycogen that can be highlighted by PAS that disappears with diastase digestion. The cells typically show strong cytoplasmic membrane staining for PLAP. Recently, c-kit (CD117) and OCT4 positivity (Figure 13.7) has been reported in up to 92% and 100% of dysgerminomas respectively. Tumor cells are frequently positive for vimentin, LDH, and neuron-specifi c enolase (NSE). Approximately 30% of dysgerminomas contain scattered cells positive for cytokeratin. They are negative for EMA, CEA, S-100 protein, leukocyte common antigen (LCA), and AFP. Syncytiotrophoblast cells stain for β-hCG.
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本例表达PLAP、CD117,考虑为无性细胞瘤,浸润淋巴细胞为T细胞,CD20未见阳性表达,支持诊断,子宫腔内外各见一肿瘤,考虑转移可能性大,但患者术后失访,不清楚卵巢及其他可能发生此肿瘤的组织器官检查情况。原单位最初诊断为透明细胞癌,未考虑到此病的可能性,且不具备免疫组织化学检查技术条件,导致此例是原发还是转移成为一个悬案。