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panzenggang 离线
Thanks for this interesting case. Tumor cells form nests in a background of small lymphocytes. The tumor cells are intermediate in size with round nuclei, fine chromatin and small nucleoli. My differential diagnosis:
1. Lymphoepithelioma-like carcinoma. I favor this one. please do cytokeratin and P63
2. Non-Hodgkin lymphoma, particularly DLBCL. Please do CD45, and T-/B-cell markers.
Thanks for this interesting case. Tumor cells form nests in a background of small lymphocytes. The tumor cells are intermediate in size with round nuclei, fine chromatin and small nucleoli. My differential diagnosis:
1. Lymphoepithelioma-like carcinoma. I favor this one. please do cytokeratin and P63
2. Non-Hodgkin lymphoma, particularly DLBCL. Please do CD45, and T-/B-cell markers.
有时口咽环DLBCL和低分化癌形态学很难鉴别,需要免疫组化辅助诊断。