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- Rectal polyp
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panzenggang 离线
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panzenggang 离线
- 帖子：189
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本帖最后由 于 2011-04-17 13:19:00 编辑
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Most common site of colonic carcinoid is rectum
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Gross: usually < 5 mm, round, no ulceration
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Morphology
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Islands, trabeculae, glands or sheets of monotonous cells.
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Scant, pink granular cytoplasm and round-oval stippled nuclei, small nucleoli.
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Minimal pleomorphism, minimal mitotic activity; rarely mucin secretion or anaplasia; no necrosis
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Positive stains: chromogranin, synaptophysin, neuron specific enolase, PAP (80%), CEA, hCG
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Negative stains: PSA
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DDX: prostate carcinoma (PSA+, neuroendocrine markers-)
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5 year survival 90%. Poor prognosis: 2 cm or larger, invasion of muscularis propria, 2+ mitotic figures/HPF, angiolymphatic invasion, anaplasia.
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Treatment: local excision; partial colectomy if malignant potential.
Yes. Everyone is right.
Final diagnosis: Rectal carcinoid tumor.
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Rectal Carcinoid Tumor |
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Reference: pathologyoutlines.com |
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IHC 1: synaptophysin IHC 2: chromogranin A
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名称：图1
描述：图1
名称：图2
描述：图2
