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panzenggang 离线
姓 名: | ××× | 性别: | Female | 年龄: | 55 |
标本名称: | Lymph node | ||||
简要病史: | A 55 years old female had axillary lymphadenopathy. | ||||
肉眼检查: |
panzenggang 离线
Final diagnosis: Metastatic lobular carcinoma of breast
http://enjoypath.com/hp/hp-150/hp-150.htm
Lobular carcinoma of breast may initially present as metastasis without breast symptoms. I have seen a case initially presented with ascites (Case-0390). In this lymph node, the tumor cells diffusely infiltrate the interfollicular area with relatively preserved architecture of lymph node. The tumor cells are admixed with lymphocytes, and compared with surrounding lymphocytes, they are larger with fine chromatin and small nuclei, which may mimic large cell lymphoma. However, frequent intracytoplasmic lumen is noted, and particularly in the extranodal soft tissue, there are tumor cells arranged in classic Indian file pattern.