![[已确珍]前列腺病变-1_硬化性腺病(sclerosing adenosis)图1](/sites/default/uploads/old/2007-9/user_filesuserfile19281.jpg "[已确珍]前列腺病变-1_硬化性腺病(sclerosing adenosis)图1")
![[已确珍]前列腺病变-1_硬化性腺病(sclerosing adenosis)图2](/sites/default/uploads/old/2007-9/user_filesuserfile19282.jpg "[已确珍]前列腺病变-1_硬化性腺病(sclerosing adenosis)图2")
![[已确珍]前列腺病变-1_硬化性腺病(sclerosing adenosis)图3](/sites/default/uploads/old/2007-9/user_filesuserfile19283.jpg "[已确珍]前列腺病变-1_硬化性腺病(sclerosing adenosis)图3")
![[已确珍]前列腺病变-1_硬化性腺病(sclerosing adenosis)图4](/sites/default/uploads/old/2007-9/user_filesuserfile19284.jpg "[已确珍]前列腺病变-1_硬化性腺病(sclerosing adenosis)图4")
![[已确珍]前列腺病变-1_硬化性腺病(sclerosing adenosis)图5](/sites/default/uploads/old/2007-9/user_filesuserfile19285.jpg "[已确珍]前列腺病变-1_硬化性腺病(sclerosing adenosis)图5")
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- [已确珍]前列腺病变-1_硬化性腺病(sclerosing adenosis)
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zhongshihua 离线
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| 以下是引用古城在2007-9-20 19:14:00的发言：
前列腺硬化性腺病 依据：前列腺大腺泡间密集的小腺泡；间质硬化，腺体周围有玻璃样的胶原围绕；核仁可见，但不够大<3um。 可做免疫组化染Actin、P504S及基底细胞标记HCK和P63，应出现基底细胞的肌上皮细胞化生Actin阳性。 鉴别诊断：高分化前列腺腺泡细胞癌。（大核仁；P504S阳性；Actin、HCK和P63阴性） 很好的病例，谢谢！ |
古城, Excellent job!
Besides histopathologic features you described, another important clinical corelation is the normal PSA level and almost always incidental finding in TURP specimen.
- 不坠青云之志，长怀赤子之心
answer: prostatic sclerosing adenosis. In sclerosing adenosis, the basal cells acquire myoepithelial phenotypes such as S100 and smooth muscle actin expression.
是硬化性腺病, 这个病的基底细胞会获得一些肌上皮细胞的特点: 如表达S100 和 ACTIN. 免疫组化的图过2天贴上来 (放在办公室的电脑上了).
我上回在泌尿病理的一个帖子说了: 泌尿系有2个病腺体周围有玻璃样的胶原围绕--> 肾源性腺瘤和硬化性腺病. Last time I mentioned in a post in the session of urologic pathology: there are 2 lesions in the genitourinar tract that have hyalinzing base membrane surrounding glands---nephrogenic adenoma and prostatic sclerosing adenosis.
古城的分析很好. xie xie!
