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- 筛窦肿瘤
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zhongshihua 离线
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Some of the low power figures show an architectural pattern of an inverted Schneiderian papilloma. Other low power figures, however, show focal surface erosion/ulceration and irregular epithelial nests of varying sizes surrounded by desmoplasia consistent with stromal invasion. Medium- and high power figures clearly show a high grade invasive carcinoma. A superficial layer of benign ciliated columnar epithelia focally overlies multiple layers of dysplastic cells underneath, an observation in support of a pre-existing inverted Schneiderian papilloma. The neoplastic growth is endophytic and not exophytic/papillary. Nomenclature of this type of malignancy is not standardized, and the best term in my opinion is Schneiderian carcinoma because it delivers the association with inverted Schneiderian papillomas. However, the current (2003) WHO classification of head and neck tumors would put this case under the category of non-keratinizing squamous cell carcinoma. It is, in my opinion, a high grade carcinoma.
聞道有先後,術業有專攻
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zhongshihua 离线
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本帖最后由 于 2006-11-04 12:32:00 编辑
学习mjma老师的讲解并试译如下：
部分低倍图像显示内翻性乳头状瘤的结构。然而其它低倍图像显示，灶性表面糜烂/溃疡形成，大小不一、形状不规则的上皮巢围以促结缔组织反应的间质，符合间质浸润。中、高倍图像清楚显示高级别浸润癌。下层的多层异型细胞之上，局灶性被覆良性纤毛柱状上皮，此观察支持先前存在内翻性乳头状瘤。 肿瘤呈内生性生长，而不是外生性/乳头状。这一型恶性肿瘤的命名尚无统一标准，我的观点是最好称为施奈德氏癌（内翻性乳头状癌？请马老师审核），因为它伴随着内翻性乳头状瘤。然而，新版（2003）WHO头颈部肿瘤分类将这例放在非角化型鳞癌中。我的观点：高级别癌。
华夏病理/粉蓝医疗
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