赞同海上明月老师！
有点晕。还想了解更多的IHC指标，如S-100、CK、CD34、肌上皮标记等等、 
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- about 50 y/f breast core bx (cqz-33, 7-1-2001
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本帖最后由 于 2010-07-13 12:34:00 编辑
免疫组化判读：
导管癌（或正常导管）： E-cadherin和p120均呈膜阳性。小叶病变：E-cadherin不着色（或比对照减弱），p120胞浆强阳性。
参见Dr.cqzhao以前的教学病例：http://www.ipathology.com.cn/forum/forum_display.asp?classcode=129&keyno=111923&pageno=2
14楼图2 E-Ca弱阳性（不是完整的膜阳性），而p120胞浆强阳性。因此更可能是小叶癌。HE形态确实很难判断，免疫组化没看到肌上皮标记物之前，还不敢下结论。
谢谢Dr.cqzhao！
华夏病理/粉蓝医疗
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This is my collegure's case. Myoepithelial marker stains were not performed even though I think it is reasonable to do the stain. However you check the ae1/ae3 stain carefully, you will notice the pattern like invasive cancer, but not like sclerosing adenosis. I agree with most of you. It may be a lobular cancer. But it is not easy to interpretation of e-cad and p120 stains in this inflammatory background. So the case was released as invasive mammary carcinoma. The detailed type is defered for further evaluation.
