Giant cell granuloma can be central or peripheral depending on its intra or extraosseous location. Histologically they can look alike and are composed of fibrous stroma with numerous capillaries with endothelial proliferation and variable number of multinucleated giant cells. Foci of hemorrhage with hemosiderin laden macrophages are characteristic findings. Mitoses can be seen.
Differential Diagnoses:Aneurysmal bone cyst of the mandible,Giant cell tumor,Malignant giant cell tumor
Giant cell granuloma can be central or peripheral depending on its intra or extraosseous location. Histologically they can look alike and are composed of fibrous stroma with numerous capillaries with endothelial proliferation and variable number of multinucleated giant cells. Foci of hemorrhage with hemosiderin laden macrophages are characteristic findings. Mitoses can be seen.
Differential Diagnoses:Aneurysmal bone cyst of the mandible,Giant cell tumor,Malignant giant cell tumor