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This mixture of two antibodies works on formalin-fixed, paraffin embedded tissue.
Immunohistochemical expression
AE1 reacts with most acidic (type I) cytokeratins (K10, 15, 16 and 19) while AE3 recognises all known basic (type II) cytokeratins.
This mixture of antibodies reacts with almost all epithelia without showing cross-reactivity with other intermediate filaments.
hepatocellular carcinoma
Transitional cell carcinoma
Small cell carcinoma
Carcinoid tumour
Pleomorphic adenoma (epithelial component)
Thymoma
Mesothelioma (including sarcomatoid component)
Germ cell tumours, except seminoma
Epithelioid sarcoma
Leiomyosarcomas may be positive
AE 1/3 is advantageous in the detection of lymph node micrometastases. It shows less frequent immunoreactivity with reticulum cells than do other pan-cytokeratins or Cam 5.21.
shanghainese 离线
以下是引用在2007-7-3 17:55:00的发言:
在我的主页里修改个人资料里会有个人签名,如下图,当我们浏览你的任何文贴时也学习了,如何?
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以下是引用tiannuo在2007-7-8 0:36:00的发言:
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以下是引用tumor在2007-7-8 0:44:00的发言:
干嘛去抢别人的CD117啊,你自己有啊,CD197运用好久了的 |