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Benign endocervical and endometrial polyps that present at the cervical os are prone to erosion and ulceration. This, in turn, leads to degenerative, reparative, and squamous metaplastic changes in the native glandular epithelium, which can mimic neoplasia. In addition, cell groups sampled from the polyp surface may also show macronuclcoli, mitoses, hyperchromasia,cellular crowding, and a slight loss of polarity. Overinterpretation is avoided by noting that the abnormal cells are usually limited to only a few, cohesive, two-dimensional cell groups showing smooth nuclear borders and finely granular, evenly distributed chromatin. A diagnosis of ASC-US or AGC may be warranted in some cases and may lead to the initial discovery of the polyp .
摘自《Gynecologic Cytopathology》
出现在宫颈外口的良性子宫颈管和内膜息肉容易糜烂并溃疡形成。这样导致腺上皮变性,修复,鳞化,都能有假瘤样。而且,来自于息肉表面的细胞团可以表现核大,有丝分裂,深染,细胞拥挤和轻度的失去极性。避免过度诊断那些不是异常的细胞,他们一般表现为仅少量,粘合成团,二维的细胞团有光滑的细胞边界和细颗粒,均匀分布的染色质。诊断ASCUS和AGC可能在一些息肉的病例中是正确的。 摘自《妇产科细胞病理学》。
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