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Allograft kidney with acute cellular rejection and atypical glomerular changes under EM

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楼主 发表于 2010-01-13 01:08|举报|关注(0)
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姓    名: ××× 性别:  Female 年龄:  61
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简要病史: The patient is a 61-year-old female with past medical history of end-stage renal disease secondary to polycystic kidney disease status post deceased donor allograft in 2006, with history of hypertension, nonischemic cardiomyopathy.
肉眼检查:  

The formalin fixed specimen was sent to an outside institution for coverage while I was out of

town. The paraffin section diagnosis is as follows:

 

Allograft kidney, needle biopsy:

A.                Mild to moderate acute cellular rejection, Banff type 1B.

B.                 Moderate chronic allograft nephropathy, with focal and segmental glomerulosclerosis involving two of five glomeruli (2/5).

C.                 Peritubular capillary inflammation; the formalin fixed tissue section shows DIFFUSE C4d staining in the peritubular

             capillaries.

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