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Modified Scheuer histologic scoring system
Grade |
Portal/Periportal |
Lobule |
Stage |
Degree |
0 |
None or minimal portal without periportal (interface) |
None |
0 |
None |
1 |
Portal inflammation without periportal |
Inflammation but no liver cell necrosis |
1 |
Minimal portal fibrosis with extension into lobule seen only with reticulin |
2 |
Mild (spotty) periportal (limiting plate) inflammation |
Focal or unicellular necrosis |
2 |
Early periportal fibrosis or rare portal-portal septa with intact architecture |
3 |
Moderate portal/periportal inflammation, usually <50% of limiting plate |
More extensive necrosis, but no or minimal bridging |
3 |
Septal fibrosis with architectural distortion, including nodule formation but not cirrhosis |
4 |
Severe periportal and bridging inflammation |
Extensive necrosis including multifocal bridging |
4 |
Probably or definitely cirrhosis |