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35 Year old with testicular nodule

stevenshen 离线

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楼主 发表于 2009-09-20 07:10|举报|关注(0)
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姓    名: ××× 性别: Male 年龄: 35
标本名称: testis  
简要病史: Painless testicular nodule
肉眼检查:  
Your differential diagnoses and frozen section diagnosis
  • 35 Year old with testicular nodule图1
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  • 35 Year old with testicular nodule图2
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  • 35 Year old with testicular nodule图3
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×参考诊断
腺瘤样瘤

stevenshen 离线

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1 楼    发表于2009-10-17 07:36:00举报|引用
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I do think that this is a tough case...You just have to think about it.

The diagnosis is: adenomatoid tumor (cellular)

The differential diagnoses that were mentioned are all very appropriate.

The helpful features are:

1. usually small, well circumscribed nodule

2. paratesticular rather than intra-testicular location (can happen)

3. cells with vacuoles

4. no cytologic atypia or mitosis

5. can have dense stroma, smooth muscle, lymhphoid infiltrate

6. of course calretinin is helpful

 --------------------------------------------------------------------------------------------------

Please share your experience and interesting case!

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stevenshen 离线

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2 楼    发表于2009-10-13 09:13:00举报|引用
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 支持细胞肿瘤 is a good guess! I hope you will agree that morphogy is very unique with haylinzed material around epithelial-like cord or trabeculae of cells. Differential diagnoses might be include:

1. Leydig cell tumor

2. Metastatic carcinoma

3. Malignant mesothelioma

4. Adenomatoid tumor

5. Any others?

what's your top choices and what stains (if necessary) do you want the most?  

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