腺体共壁，细胞 异型性不太大。图4似浸润性生长，图6脉管内似是癌栓。高级别上皮内瘤变，不排除浸润癌。

• Not sure either; but would venture to give my best guess
• We don't know where the anastomotic nodule, but there is clearly high grade dysplasia or intramucosal carcinoma (some don't use the terminology); no clear cut evidence of desmoplasia; some irregular angulated glands; most worry about Fig. 4 - suspicious for invasion.
• Also like to hear other's opinion.
• Please give your final diagnoses or slide consultation diagnoses.