考虑高分化软骨肉瘤。

Please provide the patient's age and gender if you can. This looks like a large skull base tumor. Uploaded photos raise two differential diagnoses - low grade chondrosarcoma and chondroid chordoma. I favor the former, but since the two mimic each other so much cytokeratin (AE1) immunohistochemical stain should be done. AE1 is strongly positive in chordoma and entirely negative in chondrosarcoma. Skull base tumors like these two are very difficult to treat because they respond poorly to chemotherapy or radiation. Surgical excision is impossible in most cases. The best excellent neurosurgeons can achieve in most cases is debulking. The residual tumor will continue to grow slowly and, in the case of chordoma, will metastasize or seed the neuraxis via CSF circulation.

 聪明啊!一次成功!