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Thank you, Frankbj. The case you posted is great. The immunohistochemical stain for C4d is not easy to interpret. If your interpretation is "positive in peritubular capillaries", I favor the diagnosis of "suggestive of acute antibody-mediated rejection, type 2 or 3 (?). There is early endoarteritis, not a true v3 lesion. I don't see thrombosis (what about in the #1 photo?). Please let us know your final diagnosis and your patient's response to the treatment.