Rosai-Dorfman Disease present in breast (cqz 16)

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楼主发表于 2009-04-09 12:33|举报|关注(1)
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姓名：	×××	性别：	年龄：
标本名称：
简要病史：
肉眼检查：

40 y women with breast lesion, biopsy

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标签：乳腺Rosai-Dorfman病

本帖最后由于 2009-04-17 05:39:00 编辑

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1 楼发表于2009-04-23 11:09:00举报|引用
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Ocassionally notice that the photos in this section do not have protection markers. Why? we need to add the markers. Thanks, cz

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2 楼发表于2009-04-23 11:07:00举报|引用
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还是请Dr.zhao在您方便的时侯给大家讲一讲有关RDD的诊断和治疗原则。

笃行者 ,

I am gynecologic/breast pathologist and cytopathologist, do not read other surgical specimens. This is my previous AFIP case. Frequently speaking I needed to review the text book before I pasted the case here. So I am not qualified to talk RD in more details. sorry. cz

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3 楼发表于2009-04-17 05:38:00举报|引用
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The differential dx of RDD also includes Langerhans' cell histoiocytosis which is positive for S-100.

Which mark can distingush these two?

Are the lymphocytes T or B or mixed?

Are the plasma cells polyclonal or monoclonal?

The etiology of RDD remains unknown.

What are the most two likely possibilities?

Is there effective treatment?

What is the prognosis?

What age and what race are more common for RDD?

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4 楼发表于2009-04-17 05:22:00举报|引用
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本帖最后由于 2009-04-17 05:22:00 编辑

Excellent summary. Thanks, Abin.

cz

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5 楼发表于2009-04-16 13:12:00举报|引用
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以下是引用笃行者在2009-4-9 20:34:00的发言：

这种图像在乳腺还真没见过，如果在软组织我倒想到Rosai-dorfman病

You are great.

RD is rare in breast. I saw three breast cases for one year when I was at AFIP. In fact i work in Magee women's hospital (about 30,000 surgical cases with half for breast and half for gyn) for three years and we do not have any breast RD case. AFIP is a consulting institute and this is why there are many rare and difficult cases.

Dr. 笃行者 can tell us why you think it is RD in your first impression?

Also please have a brrief summary about RD, clinical, morphologic, IHC, treatment, prognosis et al.

Thank,

cz