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姓 名: | ××× | 性别: | 女 | 年龄: | 24 |
标本名称: | 宫颈活检 | ||||
简要病史: | ASC, high rish HPV positive | ||||
肉眼检查: |
Herpetic cervicitis is the diagnosis. Good job! Thanks, Dr. Yang. My first time posting a case, very fun!
疱疹病毒包涵体的特征:细胞核包涵体,3M:multinucleation, molding, margination of chromatin, 包涵体呈毛玻璃样,ground glass inclusion. 疱疹一般引起组织炎症坏死(pink material you see in all 4 photos), that is why i went to high power to look for inclusion bodies. We see inflammation in cervix all the time, but don't see necrotic pink material much. Then i found perfect HSV changes. 很遗憾图片没镜下漂亮清楚。The findings i saw under microscope are diagnostic for herpetic cervicitis, concurred by my colleagues. I see tons of cervical biopsies every day in the past 3.5 years, this is my first time seeing HSV in biopsy. I see HSV in pap smears very often..
疱疹宫颈炎一般在组织切片上看不到包涵体,但宫颈涂片上很常见。见上二图。上一图是疱疹食道炎,我做住院医生时器官移植病人很多,经常见疱疹。
此病人08年8月HSV-1抗体阳性,HSV-2阴性。太久了,没帮助。几周前宫颈涂片也无疱疹。HSV-1主要感染面部如嘴唇,HSV-2主要感染宫颈阴道外阴等。她没怀孕。
巨细胞病毒包涵体在胞核和胞浆,疱疹只是胞核。妊辰反应是大细胞有很多胞浆,胞核无异常,和妊辰期蜕膜一样。