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- 0900993卵巢肿瘤够癌吗?
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zhongshihua 离线
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Borderline mucinous tumor of ovary, with foci suspicious for intraepithelial carcinoma (high power views show striking nuclear atypia). No invasion identified on shown photomicrographs. Glands within stroma look like invagination rather than true stromal invasion.
Please let me know why some people think it is serous! I think intracytoplasmic mucin is apparent. Serous cells have scant clear cytoplasm. Here we see abundant mucinous cytoplasm. Some pathologists including experienced old pathologists in China told me they call serous tumor when the cyst fluid is clear! Wrong wrong wrong!! We check cytoplasm in the cells to determine mucinous or serous.
Borderline tumor with intraepithelial carcinoma is different from invasive carcinoma, the former with better prognosis. This is borderline tumor because of nuclear stratification and papillary protrusion into cystic cavity.
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We would submit the entire hemorrhagic area or any solid area for histologic examination. Because mucinous tumor sometimes are mixed in degree of malignancy (benign-borderline-malignant all present in a single specimen), some pathologists submit the entire specimen if not too large.
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lanyueliang 离线
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本帖最后由 于 2009-02-12 09:56:00 编辑
| 以下是引用mingfuyu在2009-2-12 8:42:00的发言：
Borderline mucinous tumor of ovary, with foci suspicious for intraepithelial carcinoma (high power views show striking nuclear atypia). No invasion identified on shown photomicrographs. Glands within stroma look like invagination rather than true stromal invasion. Please let me know why some people think it is serous! I think intracytoplasmic mucin is apparent. Serous cells have scant clear cytoplasm. Here we see abundant mucinous cytoplasm. Some pathologists including experienced old pathologists in China told me they call serous tumor when the cyst fluid is clear! Wrong wrong wrong!! We check cytoplasm in the cells to determine mucinous or serous. Borderline tumor with intraepithelial carcinoma is different from invasive carcinoma, the former with better prognosis. This is borderline tumor because of nuclear stratification and papillary protrusion into cystic cavity. |
Agree with Dr. Yu.
Mucinous bordline tumor (or M-LMP) with intraepithelial carcinoma. Make sure you have enough sections.
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If the photos represent the entire lesion and adequate sampling for microscopic examination has been achieved, I would favor this being a borderline mucinous neoplasm of ovary. However, mucinous neoplasms of ovary are tricky and careful, thorough sampling for microscopic examination is essential.
聞道有先後,術業有專攻
